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09/15/2025 Paul Kesselman, DPM
Increased Risk of Fatal Falls
A recent article in September 7, 2025 NY TImes entitled Why Are More Older People Dying After Falls, is a must read for every physician, no matter their specialty. The NY Times article points out a threefold increase in fatal falls over the last thirty years. This compared to a decreased or steady number of fatal falls per capita in other countries.
The reason cited by both the NY Times and its source is the increased reliance on Fall Risk Increased Drugs(FRID) in the U.S. JAMA News while a much lengthier read, provides a substantial amount of statistical analysis and is the foundation of the findings cited in the NY Times article..
Having no other motive but to decrease falls in our most fragile patients, it is imperative to look into whether our elderly patients are at a higher risk of falling due to taking FRID, whether those medications are prescription or non- prescription. Gabapentin,one FRID identified prescription medication, often prescribed by podiatrists and other physicians is often the go to drug for chronic pain.
With the various initiatives to reduce opioid dependency, Gabapentin (and similar medications) are often used for patients with pain particularly of a neurogenic etiology (e.g. diabetic neuropathy, radiculopathy, etc.). They have all been identified as FRID.
Many of our patients also take other FRID including proton pump inhibitors, diazepines and beta blockers. While those latter gabapentin certainly is. Other medications used to treat urinary frequency, OTC antihistamines for both as a sleep aid and for allergy relief, with the latter sometimes prescribed by podiatric physicians are also on the list of FRID. It is no wonder the US has seen an increase in fatal falls over the past decade.
Adding to this fatality risk is the increased reliance on various anticoagulants (direct and non direct agents) for a variety of cardiovascular and neurological issues, one has a recipe for a fall in our elderly patients being the last thing that happens to them.
Having known several relatives and relatives of friends who lost loved ones due to a fatal fall and perhaps due to FRID with anticoagulants, it is imperative that any fall prevention discussion brings up the FRID +anticoagulant issue. Speaking with the doctors who have prescribed these medications is mandatory.
I had my then 90+ year old dad's cardiologist discontinue him from coumadin, because he had not had an arrythmia for 7 years prior. He was simply on it due to a previous one-time event. Was this a rational reason or not? A discussion with the cardiologist and my dad came to the conclusion that while a risk, it was a risk worth taking. He fell many times after that yet he never sustained a life ending fall!. Who knows what would have happened from the many times he struck his head in subsequent falls?
Yes, addressing proper footwear, identifying other issues requiring referral (e.g. ophthalmology and visual impairment, neurology and neuromuscular issues) and removing hazards from the home are also important in particular for patients who are at increased risk of falling and particularly for those where a fall may be deadly. Patients living alone are also at higher risk for falls and fatal falls as well.
Enlisting social services, referral to physical and occupational therapy and enlisting other modalities are also prudent discussion points to have with your patients and their caregivers.
There certainly may be times when an AFO and other ambulatory assistive devices (cane, walker, etc) may also be appropriate, but that should occur only after a thorough fall risk assessment is conducted and all the issues involved identified. Prescriptions and orders for AFO and walker will no doubt fail if the primary reason for the patient's fall risks are not properly addressed.
Paul Kesselman, DPM, Oceanside, NY
Other messages in this thread:
09/16/2025 Bob Smith, DPM, MSc, RPh
RE: Increased Risk of Fatal Falls (Paul Kesselman, DPM)
I would like to thank and applaud Dr. Kesselman for his communication centered on the increased risk of fatal falls. I also encourage all medical professionals to not only explore these recent suggested literature sources. Twenty-five years ago, I started researching and developed a narrative that was published as: Smith RG. Fall- contributing adverse effects of the most frequently prescribed drugs. J Am Podiatr Med Assoc. 2003 Jan-Feb;93(1):42-50. The foremost reason, purpose of this narrative was to document the possible plausibility and causality of medication inducing adverse effects. Given the advances in technology and leaders in our profession indicate that podiatrists should be the leading professionals to identify and prevent falls among our most vulnerable populations.
In July of 2025, I began a systematic literature review to obtain actual statistics and numbers of medications that induce fall injury. I have obtained a wealth of information described as The FDA adverse event reporting system database, drug monographs describing the pharmacokinetics properties, The AGS Beers Criteria 2023, and auditory and vestibular side-effects of FDA- Approved Drugs for Diabetes, and medication that affect balance. A further goal for obtaining this objective data is to develop an electronic predicative tool. Moreover, with any tool that prevails, the properties of clinimetrics is my hope.
Perhaps podiatrists can integrate assessments for fall risk in their prehabilitation; that provides patients with exercise programs to optimize strength and range of motion while also increasing patient knowledge of and exposure to interventions that they will receive after surgery. Andrews ,et al’s (2022) retrospective cohort study design at a single institution found a high incidence of postoperative falls in the first 6 weeks after foot and ankle surgery. They underscored that baseline antidepressant uses and higher 2-week VAS pain scores were associated with post-operative falls. It is acknowledged that there are check- lists for inpatient and nursing home residences. My hope is that this revisiting of fall- contributing adverse effects of the most frequently prescribed drugs twenty-five years later and the development of an electronic predictive tool available to all healthcare professions for all patient populations. Bob Smith, DPM, MSc, RPh, Ormond Beach, FL
09/15/2025 Paul Kesselman, DPM
Increased Risk of Fatal Falls
A recent article in September 7, 2025 NY TImes entitled Why Are More Older People Dying After Falls, is a must read for every physician, no matter their specialty. The NY Times article points out a threefold increase in fatal falls over the last thirty years. This compared to a decreased or steady number of fatal falls per capita in other countries.
The reason cited by both the NY Times and its source is the increased reliance on Fall Risk Increased Drugs(FRID) in the U.S. JAMA News while a much lengthier read, provides a substantial amount of statistical analysis and is the foundation of the findings cited in the NY Times article..
Having no other motive but to decrease falls in our most fragile patients, it is imperative to look into whether our elderly patients are at a higher risk of falling due to taking FRID, whether those medications are prescription or non- prescription. Gabapentin,one FRID identified prescription medication, often prescribed by podiatrists and other physicians is often the go to drug for chronic pain.
With the various initiatives to reduce opioid dependency, Gabapentin (and similar medications) are often used for patients with pain particularly of a neurogenic etiology (e.g. diabetic neuropathy, radiculopathy, etc.). They have all been identified as FRID.
Many of our patients also take other FRID including proton pump inhibitors, diazepines and beta blockers. While those latter gabapentin certainly is. Other medications used to treat urinary frequency, OTC antihistamines for both as a sleep aid and for allergy relief, with the latter sometimes prescribed by podiatric physicians are also on the list of FRID. It is no wonder the US has seen an increase in fatal falls over the past decade.
Adding to this fatality risk is the increased reliance on various anticoagulants (direct and non direct agents) for a variety of cardiovascular and neurological issues, one has a recipe for a fall in our elderly patients being the last thing that happens to them.
Having known several relatives and relatives of friends who lost loved ones due to a fatal fall and perhaps due to FRID with anticoagulants, it is imperative that any fall prevention discussion brings up the FRID +anticoagulant issue. Speaking with the doctors who have prescribed these medications is mandatory.
I had my then 90+ year old dad's cardiologist discontinue him from coumadin, because he had not had an arrythmia for 7 years prior. He was simply on it due to a previous one-time event. Was this a rational reason or not? A discussion with the cardiologist and my dad came to the conclusion that while a risk, it was a risk worth taking. He fell many times after that yet he never sustained a life ending fall!. Who knows what would have happened from the many times he struck his head in subsequent falls?
Yes, addressing proper footwear, identifying other issues requiring referral (e.g. ophthalmology and visual impairment, neurology and neuromuscular issues) and removing hazards from the home are also important in particular for patients who are at increased risk of falling and particularly for those where a fall may be deadly. Patients living alone are also at higher risk for falls and fatal falls as well.
Enlisting social services, referral to physical and occupational therapy and enlisting other modalities are also prudent discussion points to have with your patients and their caregivers.
There certainly may be times when an AFO and other ambulatory assistive devices (cane, walker, etc) may also be appropriate, but that should occur only after a thorough fall risk assessment is conducted and all the issues involved identified. Prescriptions and orders for AFO and walker will no doubt fail if the primary reason for the patient's fall risks are not properly addressed.
Paul Kesselman, DPM, Oceanside, NY
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