08/12/2025    

RELEVANT RESEARCH

Intralesional Cidofovir Promising for Treating Refractory Warts

 

A case series of children aged 7-17 years found that treatment with intralesional cidofovir was effective in healing recalcitrant warts, with several children experiencing complete resolution. The results were presented in a poster session at the Society for Pediatric Dermatology (SPD) 2025 Annual Meeting. “Treatment was well tolerated, and we were able to control pain,” study author Vivian Iloabuchi, BS, a third-year medical student at the Mayo Clinic Alix School of Medicine in Scottsdale, Arizona, told Medscape Medical News.

 

The results reported at the SPD meeting were from a case series of seven children aged 7-17 years with three or more cutaneous warts located on the extremities that had not responded to salicylic acid, cryotherapy, Candida antigen injections, oral cimetidine, and/or pulsed dye laser. Cidofovir 15 mg/mL was injected into each wart, at doses ranging from 2 mg to 13.5 mg, with a total dose per session from 4.5 mg to 30 mg. 

 

Source: Roxanne Nelson, Medscape [8/1/25] via Dr. Al Musella