04/20/2021    

RELEVANT RESEARCH

Nonavalent HPV Vaccine for the Treatment of Multiple Recalcitrant Warts

 

A cohort of 45 adults with recalcitrant plantar or periungual warts was treated with the recombinant 9-valent human papilloma virus (HPV) vaccine at 0, 2, and 6 months. Complete clearance 3 months after the final vaccination dose was seen in 62.2% of patients, while 8.9% had a partial response, and 28.9% showed no response. The mean time to response was 12.8 weeks after the first injection. In the complete response group, no recurrence was observed, but the follow-up time was not specified.

 

In some patients, a course of the 9-valent HPV vaccine may lead to complete clearance of recalcitrant warts. Further prospective trials would be useful to confirm these findings, but this treatment modality can be added to the existing array of wart treatments.

 

Source:  Margaret Hammond, MD, Practice Update [4/15/21] Via Dr. Allen Jacobs