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01/27/2017 David E. Samuel, DPM
Nerve Biopsy on a Diabetic? (John M. Hurchik, DPM)
Several years ago, better vitamin therapy was introduced by a few companies that started showing better efficacy for diminishing neuropathic pain. You purchase the vitamins, and resell them to your patients. You make a little on the vitamins and many times, patients feel better and are happy.
Good clinical studies on it and biopsy, I'm sure, played a roll in determining what the vitamins ultimately did to warrant a trial with them. We have used these vitamins and some have seemed to give some moderate improvement and some have also not been helpful. It just depends on the individual patient how it does for them.
They then developed a biopsy to show pre- and post-vitamin therapy, how many new nerve fibers were seen that was heavily marketed to the practices. This was a revenue generator for both the lab and the office performing the biopsy, but really of limited value for the patient. The bottom line is that if the vitamins were working, the patient would feel better, and who cares how many new nerve fibers are present. If they didn't feel better, again whether more fibers are seen means very little if they don't feel any better.
If you are treating a patient in the office that has some mild erythema to their hallux from an ingrown nail, and you opt to use some keflex, post nail removal and the pain and redness diminish, would you order lab work to show the white count went down? I bet if the insurance companies paid the office anything for that WBC test from a simple in-office finger stick, a whole bunch would be done vs. doing one once in a while for a patient with a larger wound that tells you they didn't feel well.
We all need to be more prudent with tests we order as well as modalities available. Just because you can doesn't mean you should. A small punch biopsy is easy and relatively simple until it gets infected or your diabetic patient with moderate edema now gets a large wound or cellulitis from a 'simple' punch. We have all seen the nightmare scratch that leads to major necrosis or bruise from the car door that becomes a crater in someone's leg or ankle.
If issues arise from necessary studies that lead to better overall care for the patient, then those things happen and for me easier to accept. But I am not sure why I need to know microscopically there is improvement if the patient tells me they feel better from the treatment, and even a small biopsy can pose any risk. Would you biopsy your mom if she told you she loves how the vitamins made her feel or just give her more vitamins?
Insurance companies will certainly catch on at some point and this and so many other things we do will just make it more difficult for all of us to get needed treatments paid for when they are now reviewing cases to prove "unnecessary use" of some necessary things, as everything gets more scrutinized. Does anyone remember when insurance companies paid us pretty well for orthotics? That became a license to prescribe them for tinea pedis and bye bye orthotic coverage.
Do you need an ultrasound to inject a plantar fascia or put a 25g 1.5 inch needle in an ankle? If you do, I'm thinking workshop on injections vs billing for an ultrasound. Clearly we can show many examples of these types of, what I personally believe is over utilization, that makes it harder and harder to get reimbursement for all of us.
I'm just saying be prudent with studies and making conscious efforts to save some money ordering less as well as putting patients through less and maybe in a small way improve better use of healthcare dollars.
David E. Samuel, DPM, Springfield, PA
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01/28/2017 Bradley Bakotic, DPM, DO
Nerve Biopsy on a Diabetic? (John M. Hurchik, DPM)
I'm a bit confused by the post related to ENFD by John Hurchik, DPM and some of the subsequent responses, particularly that offered by Eliot Udell, DPM, who seemed to imply that clinical doctors, and their labs, are doing ENFD testing strictly for "massive" financial gain, rather than optimal patient care.
First let me say that I have been informed that Dr. Hurchik did intend for his note to take the negative tone that it seemed to. Secondly, those that believe that a punch biopsy pays a "massive" amount of money, probably have never done a punch biopsy. The "massive" reimbursement for a punch biopsy is about $85.00. It might buy you dinner at a two star restaurant, if you don't order a glass of wine. On the lab side, it is the most labor intensive, and lowest margin test that we run. In addition, although the test is performed at Harvard, Johns Hopkins, Stanford, and Cleveland Clinic, many payors refuse to reimburse for it at all, erroneously calling it experimental. ENFD is the best test for diagnosing, verifying, or quantifying small fiber neuropathy. That is why we offer it.
I do not know of all the cases that Dr. Hurchik is referring to; however, I can say that with respect to the most recent case, the patient did NOT present with typical small fiber neuropathy symptomatology, thereby prompting a confirmatory ENFD biopsy. Parenthetically, with all do respect to Dr. Udell, I must clarify that ENFD testing is not a nerve biopsy, it is a 3mm punch of skin.
It is absolutely true that ENFD is not for everyone, but it certainly has its indications. Many conditions, from large fiber polyneuropathy, to multiple sclerosis, to entrapment, can present with symptoms identical to those of small fiber neuropathy. Assuming that every patient presenting with stocking and/or glove discomfort has small fiber neuropathy is oversimplification. This is particularly true if the affected patient's symptoms are unconventional.
Finally, Dr. Hurchik's experience, though disconcerting, is not typical. Overall, 3mm punches from the leg are very well tolerated, even in the diabetic population. In fact, a study on the subject of ENFD complications in Europe several years ago was abandoned, because no complication came to fruition! This of course, does not mean that complications cannot occur. Additional post-biopsy care certainly should be taken when dealing with diabetic person's, or those with poor circulation. Throwing a suture, and extending the period for which the wound is kept dry, will both help to diminish the postoperative infection rate.
Bradley Bakotic, DPM, DO, Alpharetta, GA
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