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03/22/2014 Bryan C. Markinson, DPM
Notes from the Council for Nail Disorders Meeting
The Council for Nail Disorders Meeting concluded today in Denver, Colorado. The program was full of topics of interest to podiatric specialists, including onychomycosis, laser treatment, longitudinal melanonychia, and nail unit surgical techniques. I thought I would pass along some key points that were made at the meeting:
1) Treatment for onychomycosis without confirmatory culture or histology is UNACCEPTABLE. Many commented on patients with history of treatment failure who never were tested. Although some dermatologists and non-dermatology MDs treat without benefit of culture, this practice is rampant in podiatry. This issue has been debated in PM News before, and those that feel that eyeball diagnosis is okay would be in a very small minority.
2) When we see pigmented streaks in nail plates, we are often concerned about melanoma of the nail unit, and rightly so. However, several cases of non melanocytic tumors such as onychopapilloma, onychomatricoma, and Bowen’s disease of the nail matrix causing pigmented nail streaks were presented.
3) After much discussion about biopsy techniques of the nail matrix for pigmented streaks, shave biopsies of the matrix for melanoma are preferred over punches unless the width of the streak is less than the diameter of the punch. So for broad lesions 4mm or greater in the matrix, shave biopsy is preferred so that the dermatopathologist can see the entire breath of the lesion. Bertrand Richert, MD from Belgium, showed cases of large width shaves of matrix that produced no nail dystrophy, another benefit of this technique. Robert Baran, MD from France, and considered by many as the dean of nail disease science, stated that punches of the nail matrix up to 4mm will NOT produce nail dystrophy in most cases, but 4mm is the upper limit.
4) Always include the nail when submitting nail unit biopsy specimens. Several dermpath cases were presented showing the major diagnostic portion can be tagging on to the nail, especially when the nail avulsions are too traumatic. This created some controversy as many dermatologists, especially in Europe, like to leave the nail plate on the digit after matrix surgery. This was also postulated as a reason for recurrent benign streaks as the melanocytic lesion left tagging to the plate is put back over the surgical bed. My personal opinion is to send the nail along with the matrix specimen.
5) Glomus tumors of the nail units can be associated with as yet undiagnosed neurofibromatosis -1
6) Candida albicans can be a significant cause of onychomycosis, especially in nails presenting that are soft and crumbly and easily removed from the nail bed.
Bryan C. Markinson, DPM, NY, NY, bryan.markinson@mountsinai.org
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