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03/10/2014 Wm. Barry Turner, BSN, DPM
Using Nitropaste to Increase Blood Flow
In this time of studies and verifiable proof of effectiveness, I can only offer what I have seen.
I once used nitropaste on a patient, and tested perfusion with a laser Doppler. The digital perfusion increased 300% in five minutes. When I applied nitroglycerin paste as an RN (treating acute MI), we would apply the paste to a piece of paper and tape the paper to the person's chest. The PDR distinctly states "do not rub in".
I once heard that Dr. Harkless had participated in a study, but I have never seen it. I contacted the company making nitropaste. They were not interested in doing any studies.
All I can tell you is I use nitropaste on about 90% of my patients. I use it with Raynaud's, DM ulcers, ischemic digits, ASO, venous ulcers, and pretty much any wound that is responding slowly.
When I treat Raynaud's, I tell the patient to rub the nitropaste in their calf or arches 1/2 inch tid, alternating legs or 1/4 inch into both arches.
When I treat DM, ASO, or any ischemic ulcer, I tell the patient to rub in 1/2 inch tid, as near as they can to the wound, without disturbing the dressing.
For venous stasis, I instruct the patient to rub in 1/2 inch tid behind the knee, while keeping the leg and foot in an Unna boot.
I tell my students do not be neglectful of the edema that Nitroglycerin paste causes. If the edema becomes problematic, use an Unna boot or some form of limb edema restriction. Using an Unna boot on a patient with an ABI less than 0.6, I was taught to be a no-no. Using the Unna boot with nitropaste, I have never had an issue.
I am a firm believer that majority of venous stasis wounds are of mixed etiology and I have seen some amazing results with nitropaste.
Before I prescribe the patient nitropaste, I do a trial in my office. I get a BP, the systolic must be over 100 mmhq. I rub in the nitropaste, and repeat the BP in five minutes. I am "hoping" for a 20 mmhq drop in BP, but I seldom see that much.
In my 20+ years of practice, I have had one patient become problematic, one. In that case, I rubbed the nitropaste off, raised the patient's feet, until they felt better. The patient was well into her 90s and did not weigh 100 pounds. A half inch is not a very strong dose. The paste does effect the entire body, but if works strongest where it is applied. I have had headache complaints with nitropaste, maybe three times in all my years.
My rationale for rubbing in the nitropaste is that I am trying to break up calcified and hardened arteries-I want a surge effect.
Now I use multiple modalities to heal my patients, so I can not say for sure whether I can point to the nitropaste as being the causative agent, but I do see radiographic improvement of calcified arteries in my patients.
Rx NItropaste 2%, Disp 60 gm, 1/2 inch to be rubbed in xxxxx, tid (xxx=arch, calf, behind the knee...) I do avoid rubbing it in over boney prominences.
When I write an order for nitropaste for an inpatient, Nitropaste, rub in 1/2 inch to xxxx, tid, hold for SBP under 100mmhq.
Also, like narcotics, the body does develop a tolerance to nitroglycerin topical and you may need to increase the dosage. I do not recommend long-term use of nitropaste because of the tolerance issue. I will recommend oral calcium blockers to the patient's primary care doctor.
I hope this response is some help to you. Of further note, I now have the Emory cardiologist, to whom I refer many of my circulatory impaired patients, following my use of nitropaste. I lecture and direct a five tier, wound care course for the GPMA's, and I teach my students to use nitropaste as well as other medications to improved arterial and venous blood flow.
I always start my nitropaste lecture with these questions, "Have you ever cut yourself shaving?" How often does it not heal? How often does the cut get infected?" You shave, how often have you cut yourself and have the wounds not heal or get infected? Have you ever thought of why that is? My thoughts are it is directly related to the abundance of blood flow to the face. I want blood to all my wounds! And plenty of it!
Spread the word and let me know if I can be of any more assistance.
Wm. Barry Turner, BSN, DPM, Royston, GA, claret32853@ymail.com
Other messages in this thread:
03/14/2014 Wm. Barry Turner, BSN, DPM
Using Nitropaste to Increase Blood Flow (Robert Bijak, DPM)
In response to Dr Bijak's "slam" on my nitroglycerin paste protocol, I am familiar with his rude responses and judgmental behavior that is so typical for him. I will try not to take it personal. I am fairly certain in my description of my protocol using nitroglycerin paste, that I presented both sides of the discussion using this particular modality. I mentioned that the medication had a dangerous potential and cited my experience of using it on a 90-year old patient, with low body weight.
I had a similar event of hypovolemia while treating a patient when I was a cardiac nurse. That incidence dosing was a full inch, applied directly over the heart. That time was under the direction of a cardiologist while I was working in a Cardiac Cath Lab. The time I used it on that "little old lady" in my office was in an attempt to save her foot. She died shortly after the amputation. That was over twenty years ago and yes I learned from the incident. I have saved literally hundreds of limbs using that technique since then. Not one person has died.
I believe that I mentioned that I had tried to do a study, but could not find any sponsors, so I recorded my experience and presented it just as that, "my experiences","my protocol".
I believe that I commented on hearing about a study, but was unable to verify it.
This medication in your hands might very well cause an MI or hypovolemic shock, but not by anyone that uses the protocol I described. I used a cardiologist to help me develop that protocol. I doubt your cardiac vascular knowledge and experience are in any way equal to mine. That is why I put together a protocol.
As far as scope of practice, I practice in Georgia. Dr. Bijak is correct what is legal in Georgia may not necessarily be legal where you practice. Regarding my practicing outside my scope of practice, I am not. Did I mention I served a decade on the Georgia State Podiatric Board? How long did Dr. Bijak serve on his state board? His statement regarding that the prescription of nitroglycerin possibly being outside the scope of practice of a podiatric physician supports my doubts regarding his knowledge of his own state's scope of practice act. I am very aware of my state's practice act. Did I mention I was the first podiatrist in Georgia to be allowed to supervise and bill for full body hyperbaric oxygen therapy when treating lower limb pathology.
My critical care experience as a RN and my over all medical background are extensive, starting with my combat medic training during the Vietnam War. I spent over five years working as a "hot shot" agency nurse in South Florida. While I was attending podiatry school, I worked in almost every ICU/MICU/SICU/CCU in the Miami/Ft. Lauderdale area. Using my knowledge to enhance my podiatric training, is just that, enhancing my ability to treat my patients within my scope of training and my state delegated restrictions.
I do not remember telling anyone to practice outside their scope of practice. Did your residency teach you how to do ankle surgery, or fix tibial-fibula fractures? Are you allowed to perform those procedures in your state? Did having the knowledge hurt you, even if you can not perform these procedures in your practice?
I understand the need for verifiable studies. I am a firm believer that testimonies are refutable and need to be verified by studies.
How many lawsuits have you had? Hmm. I have never been sued and I have practiced for over 24 years. I have people come from all over for my wound care, as I get some pretty impress results.
Do I sometimes push the envelope? Never without doing due diligence; contacting various specialist, review of literature and incorporating knowledge with common sense.
I am unsure why your ego made you feel that you needed to attack me in a less than professional manner, but I have followed your writings in the past and I am neither surprised or impressed.
Sir, when you are ready to give all to your patients, you may some day become a physician for your patients. I am willing to look outside the "box" in my attempts to heal my patients. No subterfuge. I am up front and tell them their options. I encourage second opinions.
One final word, if I might provide Dr. Bijak with a lesson in professionalism. When you disagree with other professionals, it would be more proper to contact them at their provided email address, instead of being pompous and acting like you are the moral authority of our profession. Dr. Bijak's behavior is embarrassing for our profession, or any profession for that matter.
Wm. Barry Turner, BSN, DPM, Royston, GA, claret32853@ymail.com
03/11/2014 Robert Bijak, DPM
Using Nitropaste to Increase Blood Flow (Wm. Barry Turner, BSN, DPM)
The PDR distinctly says "don't rub in", so Dr. Turner instructs patients to rub it in! Game over! Also, what defense is there for the unfounded theory he is "breaking up calcium with a surge effect." How unscientific and unproven. It makes podiatrists look bad to talk this way. In my opinion, this is dangerous, unproven advice. The fact he tried it on a 90 year old 100 pound woman speaks volumes. I don't care who he lectures to. Here's what you need to know. Podiatrists need to honestly determine if they are capable of evaluating the cerebral and cardiovascular status of a patient and concomitantly understand the pharmacology of drugs these patients may already be on, like calcium channel blockers, ACE inhibitors, etc. The danger is, you can cause a hypovolemic stroke or MI by dilating the vessels and reducing the blood pressure. Without prior sophisticated vascular testing, like carotid or vertebral artery Dopplers, you're just guessing how much the pressure can be dropped before you kill or stroke someone. Nitroglycerin is not an innocuous drug with the co-morbidities these patients present. I also do not believe a half inch strip is a low dose for some patients. Rubbing into the calf or behind the knee may even be illegal in some states for a podiatrist to do!
I think Barry Turner's "RN credential", backed by MDs in the hospital, has mistakenly led him think he has a scope beyond that allowed a DPM. His advice is anecdotal and should be followed at the DPM readers own risk. Once again podiatry's limited training and license places the practitioner in a legally dangerous gray zone, and their patients at risk.
Robert Bijak, DPM, Clarence Center, NY rbijak@aol.com
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